KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PLCH2
All Species:
4.24
Human Site:
S1223
Identified Species:
9.33
UniProt:
O75038
Number Species:
10
Phosphosite Substitution
Charge Score:
-0.2
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
O75038
NP_055453.2
1416
154668
S1223
P
D
E
L
Q
P
R
S
L
A
P
R
M
A
G
Chimpanzee
Pan troglodytes
XP_001149239
1685
188441
P1300
E
S
N
L
P
G
S
P
N
T
S
H
G
W
L
Rhesus Macaque
Macaca mulatta
XP_001085424
1423
155915
P1230
P
D
E
L
R
P
R
P
L
A
P
R
M
P
G
Dog
Lupus familis
XP_546733
1387
151432
A1205
R
A
A
S
Q
L
P
A
A
P
E
E
L
R
L
Cat
Felis silvestris
Mouse
Mus musculus
A2AP18
1501
164279
P1308
P
D
E
L
Q
P
R
P
L
A
P
R
L
T
G
Rat
Rattus norvegicus
Q62688
1096
122754
K925
L
P
P
I
A
S
L
K
Q
C
L
L
T
L
S
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Q2VRL0
637
72514
S466
V
A
L
N
F
Q
T
S
G
T
P
M
E
L
Q
Frog
Xenopus laevis
Q32NH8
758
87399
R587
D
L
N
D
G
L
F
R
Q
N
A
R
C
G
Y
Zebra Danio
Brachydanio rerio
A5D6R3
784
89362
Y613
L
P
N
G
R
C
G
Y
V
L
K
P
E
F
L
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P25455
1318
146373
S1147
A
E
K
V
L
K
T
S
Q
T
G
Q
T
K
Q
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_783611
2724
302530
S1745
P
L
E
H
S
S
S
S
H
T
P
R
K
K
S
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
46.4
94
78.7
N.A.
77.2
21.2
N.A.
N.A.
21.2
24.7
24.5
N.A.
24.2
N.A.
N.A.
26.4
Protein Similarity:
100
59.9
95.4
82.9
N.A.
81.6
36.7
N.A.
N.A.
30.7
35.3
35
N.A.
40.3
N.A.
N.A.
35.7
P-Site Identity:
100
6.6
80
6.6
N.A.
80
0
N.A.
N.A.
13.3
6.6
0
N.A.
6.6
N.A.
N.A.
33.3
P-Site Similarity:
100
6.6
86.6
20
N.A.
86.6
6.6
N.A.
N.A.
13.3
6.6
13.3
N.A.
33.3
N.A.
N.A.
33.3
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
19
10
0
10
0
0
10
10
28
10
0
0
10
0
% A
% Cys:
0
0
0
0
0
10
0
0
0
10
0
0
10
0
0
% C
% Asp:
10
28
0
10
0
0
0
0
0
0
0
0
0
0
0
% D
% Glu:
10
10
37
0
0
0
0
0
0
0
10
10
19
0
0
% E
% Phe:
0
0
0
0
10
0
10
0
0
0
0
0
0
10
0
% F
% Gly:
0
0
0
10
10
10
10
0
10
0
10
0
10
10
28
% G
% His:
0
0
0
10
0
0
0
0
10
0
0
10
0
0
0
% H
% Ile:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
10
0
0
10
0
10
0
0
10
0
10
19
0
% K
% Leu:
19
19
10
37
10
19
10
0
28
10
10
10
19
19
28
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
10
19
0
0
% M
% Asn:
0
0
28
10
0
0
0
0
10
10
0
0
0
0
0
% N
% Pro:
37
19
10
0
10
28
10
28
0
10
46
10
0
10
0
% P
% Gln:
0
0
0
0
28
10
0
0
28
0
0
10
0
0
19
% Q
% Arg:
10
0
0
0
19
0
28
10
0
0
0
46
0
10
0
% R
% Ser:
0
10
0
10
10
19
19
37
0
0
10
0
0
0
19
% S
% Thr:
0
0
0
0
0
0
19
0
0
37
0
0
19
10
0
% T
% Val:
10
0
0
10
0
0
0
0
10
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
10
0
% W
% Tyr:
0
0
0
0
0
0
0
10
0
0
0
0
0
0
10
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _